Team Europe Captain Thomas Bjørn has turned to experience as his side look to overcome a disappointing morning at Le Golf National.
Henrik Stenson, Ian Poulter and Sergio Garcia were drafted into the team shortly after Europe fell 2-0 behind following defeats for Rory McIlroy/Thorbjørn Olesen and Justin Rose/John Rahm in the opening two matches.
The trio have 17 Ryder Cup appearances and 43.5 points between them as Dane Bjørn looks to overcome a two-point deficit as United States lead 3-1 after the morning session.
Rookie Alex Noren will also be involved meaning all four players that did not feature in the fourballs will take part in the afternoon session.
McIlroy failed to register a single birdie during his round but will have the opportunity to redeem himself when he partners European talisman Poulter in the second match against Bubba Watson and Webb Simpson.
Justin Rose, who opened the morning session with Jon Rahm, will lead the foursomes alongside Swede Stenson against World Number One Dustin Johnson and Rickie Fowler - who registered the first point of the 42nd Ryder Cup for the United States.
Garcia, who need three points from becoming the all-time leading points scorer in the biennial event, will partner Noren against five-time Major Championship winner Phil Mickelson and Bryson DeChambeau in a match-up of first appearances in this year's competition.
Tommy Fleetwood and Francesco Molinari, who recorded a 3 and 1 win against Tiger Woods and Patrick Reed in the anchor match of the fourballs, will be the last foursomes pairing against Justin Thomas and Jordan Spieth.